Retatrutide
Retatrutide (LY3437943) is the triple agonist — GIP, GLP-1 and glucagon receptors, all from one molecule.
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Research use only. Not for human or veterinary use. Not FDA approved. Supplied as lyophilized powder in a sterile vial for in-vitro laboratory research by qualified professionals.
Certificate of Analysis — Batch Documentation
Batch history
Each lot is independently analyzed before release. The figures above are taken directly from the lab report for the batch currently shipping; the report itself is available on request.
Storage & Stability — Research Handling Guidance
- 🧊Lyophilized (sealed vial): store at −20 °C; typically stable 24+ months.
- ❄️Reconstituted: refrigerate at 2–8 °C and use within ~30 days.
- 🔄Avoid repeated freeze/thaw cycles — aliquot before freezing if needed.
- 🌞Protect from light — keep the vial in its carton or amber storage.
General peptide storage guidance for laboratory settings. Research use only — not for human or veterinary use.
About Retatrutide
Retatrutide, also called LY3437943, was built to act on three targets at once: the GIP receptor, the GLP-1 receptor and the glucagon receptor. The glucagon arm is what makes it different from the single- and dual-agonist peptides that came before it, and it is why so much preclinical and clinical work is currently pointed at it.
In the lab it turns up in studies of glucose handling, energy expenditure, lipid metabolism and body composition. It ships as a lyophilized powder for reconstitution in a suitable solvent under lab conditions, ≥98% purity, COA on request. Volume pricing on the larger sizes and free US shipping. Research use only, not for human or veterinary use.
What Is Retatrutide (LY3437943)?
Retatrutide (INN: LY3437943, CAS: 2381089-83-2) is an investigational triple incretin receptor agonist developed by Eli Lilly. It is the first peptide in its class to simultaneously target three receptors: the GIP receptor (glucose-dependent insulinotropic polypeptide), the GLP-1 receptor (glucagon-like peptide-1), and the glucagon receptor.
This triple-receptor mechanism distinguishes Retatrutide from earlier-generation compounds. Semaglutide activates only GLP-1 receptors; tirzepatide activates both GLP-1 and GIP receptors. Retatrutide's additional glucagon receptor agonism adds a third dimension to its metabolic research profile, making it the subject of active Phase 3 clinical investigation.
Our Retatrutide is supplied as lyophilized powder in a sterile vial, tested at ≥98% purity by HPLC with mass spectrometry identity confirmation. A Certificate of Analysis (CoA) is available for every batch. For in-vitro research and laboratory use only. Not for human consumption.
Retatrutide — Frequently Asked Questions
Retatrutide — what is it?
Retatrutide (LY3437943) is the triple agonist — GIP, GLP-1 and glucagon receptors, all from one molecule. It is identified by CAS number 2381089-83-2, a molecular weight of ~4731.3 g/mol.
How pure is Retatrutide, and is there a COA?
The batch we're shipping came back at 99.2% on HPLC. Ask and we'll send you the COA.
What does Retatrutide ship as, and how do I store it?
Retatrutide comes as a freeze-dried powder in a sterile vial. Keep it cold and out of the light until you use it. Once you reconstitute it, refrigerate it and handle it the way you would any peptide in solution.
What sizes does Retatrutide come in, and what do they cost?
Retatrutide comes in 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg. It starts at $76.50 a vial, and the bigger quantities come down from there — up to 35% off. Shipping inside the US is free, whatever you order.
Is Retatrutide for human use?
No, and that isn't a formality. Retatrutide is sold for in-vitro laboratory research by qualified professionals only. It is not for human or veterinary use, and it is not FDA approved for any therapeutic purpose.
How do I order and pay for Retatrutide?
Put Retatrutide in the cart and check out here. Pay by PayPal or Bitcoin. Orders confirmed before 2 PM ET leave the US the same day; anything later goes the next day. New to Bitcoin? There's a five-minute guide linked at checkout.
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